E2730 [Ligand Id: 14485] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| GAT1 in Human [GtoPdb: 929] [UniProtKB: P30531] | ||||||||
| GtoPdb | Binding affinity for human brain synaptosomal membranes | - | 6.15 | pKd | 710 | nM | Kd | Epilepsia Open (2023) 8: 834-845 [PMID:37052238] |
| GtoPdb | Determined as inhibition of GABA uptake in the presence of E2730 | - | 5.96 | pIC50 | 1100 | nM | IC50 | Epilepsia Open (2023) 8: 834-845 [PMID:37052238] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
