BAL-0598 [Ligand Id: 14534] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| NLRP3 in Human [GtoPdb: 1770] [UniProtKB: Q96P20] | ||||||||
| GtoPdb | Binding affinity for NLRP3NACHT determined by SPR | - | 6.71 | pKd | 193 | nM | Kd | J Exp Med (2025) 222: [PMID:40892070] |
| GtoPdb | Inhibition of NLRP3 activation in LPS stimulated THP-1 cells | - | 7.2 | pIC50 | 62.9 | nM | IC50 | J Exp Med (2025) 222: [PMID:40892070] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
