Synonyms: WLBU2
Compound class:
Peptide
Comment: PLG0206 is an engineered cationic antibacterial peptide designed using the physicochemical properties of naturally-occurring antimicrobial peptides [1]. It disrupts bacterial biofilms and is being developed by Peptilogics as a potential treatment in periprosthetic joint infections.
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References |
1. Deslouches B, Phadke SM, Lazarevic V, Cascio M, Islam K, Montelaro RC, Mietzner TA. (2005)
De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity. Antimicrob Agents Chemother, 49 (1): 316-22. [PMID:15616311] |