raxibacumab   Click here for help

GtoPdb Ligand ID: 13344

Synonyms: Abthrax | PAmAb
Approved drug
raxibacumab is an approved drug (FDA (2012))
Compound class: Antibody
Comment: Raxibacumab is a human IgG1 monoclonal antibody targeting the protective antigen (PA) component of the Bacillus anthracis toxin [2]. It has clinical approval for the prophylaxis and treatment of inhaled anthrax.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Bioactivity Comments
Raxibacumab binds with high affinity to B. anthracis PA with a Kd of 2.78 nM [1]. It does not have direct antibacterial activity.