raxibacumab   Click here for help

GtoPdb Ligand ID: 13344

Synonyms: Abthrax | PAmAb
Approved drug
raxibacumab is an approved drug (FDA (2012))
Compound class: Antibody
Comment: Raxibacumab is a human IgG1 monoclonal antibody targeting the protective antigen (PA) component of the Bacillus anthracis toxin [2]. It has clinical approval for the prophylaxis and treatment of inhaled anthrax.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
No information available.
Summary of Clinical Use Click here for help
The US FDA granted initial approval for an injectable formulation of raxibacumab in 2012. It is indicated, in combination with appropriate antibacterial drugs, for the treatment of inhalational anthrax caused by B. anthracis. Raxibacumab can also be used for prophylaxis of inhalational anthrax when alternative treatments are not available.
In the US, raxibacumab is stored in the Strategic National Stockpile for use in a public health emergency and is not commercially available.
External links Click here for help
For extended ADME data see the following:

Drugs.com