omodenbamab

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Ligands
omodenbamab

GtoPdb Ligand ID: 13379

Synonyms: 514G3

Comment: Omodenbamab is a human IgG3 monoclonal antibody that targets the cell wall component Staphylococcus Protein A (SpA) of Staphylococcus aureus [2].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.

Summary
Biological activity
Clinical data
References

References
1. Huynh T, Stecher M, Mckinnon J, Jung N, Rupp ME. (2016) Safety and Tolerability of 514G3, a True Human Anti-Protein A Monoclonal Antibody for the Treatment of S. aureus Bacteremia. Open Forum Infectious Diseases, 3. DOI: 10.1093/ofid/ofw172.1057
2. Varshney AK, Kuzmicheva GA, Lin J, Sunley KM, Bowling Jr RA, Kwan TY, Mays HR, Rambhadran A, Zhang Y, Martin RL et al.. (2018) A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia. PLoS One, 13 (1): e0190537. [PMID:29364906]

References

1. Huynh T, Stecher M, Mckinnon J, Jung N, Rupp ME. (2016)
Safety and Tolerability of 514G3, a True Human Anti-Protein A Monoclonal Antibody for the Treatment of S. aureus Bacteremia.
Open Forum Infectious Diseases, 3. DOI: 10.1093/ofid/ofw172.1057

2. Varshney AK, Kuzmicheva GA, Lin J, Sunley KM, Bowling Jr RA, Kwan TY, Mays HR, Rambhadran A, Zhang Y, Martin RL et al.. (2018)
A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia.
PLoS One, 13 (1): e0190537. [PMID:29364906]