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vixarelimab   Click here for help

GtoPdb Ligand ID: 13451

Synonyms: KPL-716 | KPL716
Immunopharmacology Ligand
Compound class: Antibody
Comment: Vixarelimab (KPL-716) is an anti-oncostatin M (OSM) receptor β subunit monoclonal antibody [1]. It disrupts both interleukin-31 and OSM signalling at the interface between immune cells and connective tissue/stromal cells, by attenuating the MCP-1 response to OSM. The effects of vixarelimab are distinct to those of an anti-IL-31 receptor α monoclonal.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11350 vixarelimab
Synonyms Click here for help
KPL-716 | KPL716
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1063
Other databases
GtoPdb PubChem SID 500839861
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