CMTX-101

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Ligands
CMTX-101

GtoPdb Ligand ID: 13582

Comment: CMTX-101 is a humanized monoclonal antibody against members of the DNABII family of bacterial DNA-binding proteins [1]. It disrupts bacterial biofilms and is being developed by Clarametyx Biosciences (Ohio, USA) as an immune-mediated therapy for serious infections associated with biofilms.

Summary
Biological activity
Clinical data
References

Bioactivity Comments
By targeting a universal component of bacterial biofilms, CMTX-101 enhances the efficacy of antibacterial agents against both Gram-positive and Gram-negative bacteria [1].

Bioactivity Comments

By targeting a universal component of bacterial biofilms, CMTX-101 enhances the efficacy of antibacterial agents against both Gram-positive and Gram-negative bacteria [1].