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Synonyms: ALN-65492 | ALN-TTRSC02 | Amvuttra® | votrisiran
vutrisiran is an approved drug (EMA, FDA & UK MHRA (2022))
Compound class:
Nucleic acid
Comment: Vutrisiran (ALN-65492) is a GalNAc conjugated double-stranded small interfering ribonucleic acid (siRNA) drug. It acts as a transthyretin (TTR) synthesis inhibitor.
We have been unable to locate a full chemical SMILES for the drug, or its HELM notation. |
Nucleic Acid Sequence  |
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(3'-5')U=G=G-G-A-U-U-U-C-A-U-G-U-A-A-C-C-A-A-G-A-R (5'-3')C=U=A-C-C-C-U-A-A-A-G-U-A-C-A-U-U-G-G-U-U=C=U |
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