AVP-21D9   Click here for help

GtoPdb Ligand ID: 13720

Synonyms: Thravixa®
Compound class: Antibody
Comment: AVP-21D9 is a fully human IgG1 monoclonal antibody that targets the protective antigen (PA) component of Bacillus anthracis toxin [1-2]. It is being developed as an intravenous treatment for anthrax following exposure to B. anthracis.
No information available.
Summary of Clinical Use Click here for help
A Phase 1 study, evaluating the pharmacokinetics and safety of a single intravenous dose of AVP-21D9 in healthy volunteers, has been completed (NCT01202695) [1].
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT01202695 Safety and Pharmacokinetics Study of Human Monoclonal Antibody (AVP-21D9) Phase 1 Interventional Emergent BioSolutions AVP-21D9 was well tolerated in healthy adult volunteers with no serious adverse events reported. 1