AER002

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Ligands
AER002

GtoPdb Ligand ID: 13723

Synonyms: AER-002 | P2G3

Comment: AER002 is a long-acting fully human anti-SARS-CoV-2 spike protein monoclonal antibody that blocks spike-ACE2 interactions, viral attachment and infection of host cells. It was isolated from post-COVID-19 patient plasma [1].

Summary
Biological activity
Clinical data
References

Bioactivity Comments
AER002 effectively neutralises infection by SARS-CoV-2 Omicron variants [1]. High binding affinity values have been established for a panel of spike proteins encoding mutations found in Alpha, Beta, Gamma and DeltaI variants (IC₅₀s 6-10 ng ml⁻¹).

Bioactivity Comments

AER002 effectively neutralises infection by SARS-CoV-2 Omicron variants [1]. High binding affinity values have been established for a panel of spike proteins encoding mutations found in Alpha, Beta, Gamma and DeltaI variants (IC₅₀s 6-10 ng ml⁻¹).