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Synonyms: ZP-8396 | ZP8396
Compound class:
Peptide
Comment: Petrelintide (ZP8396) is a long-acting (lipidated) analogue of the anorexigenic peptide amylin [1]. It was developed by Zealand Pharma for the treatment of type 2 diabetes and obesity. Amylin analogues are proposed to provide GLP-1-like efficacy with reduced propensity for side effects.
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| Bioactivity Comments |
| Amylin promotes the satiating effect through multiple pathways (decreases appetite, regulates glucose levels, slows gastric emptying). |
