GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

petrelintide   Click here for help

GtoPdb Ligand ID: 13804

Synonyms: ZP-8396 | ZP8396
Compound class: Peptide
Comment: Petrelintide (ZP8396) is a long-acting (lipidated) analogue of the anorexigenic peptide amylin [1]. It was developed by Zealand Pharma for the treatment of type 2 diabetes and obesity. Amylin analogues are proposed to provide GLP-1-like efficacy with reduced propensity for side effects.
No information available.
Summary of Clinical Use Click here for help
Petrelintide (ZP8396) is a clinical stage anti-obesity candidate [1].
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT05096598 A First-in-human Study Looking at the Safety of ZP8396 and How it Works in the Body of Healthy Trial Participants Phase 1 Interventional Zealand Pharma
NCT05613387 A Research Study Looking at the Safety of Multiple Doses of ZP8396 and How it Works in the Body of Healthy Participants Phase 1 Interventional Zealand Pharma
NCT06662539 Once-weekly Petrelintide Versus Placebo for Obesity or Overweight with Co-morbidities Phase 2 Interventional Zealand Pharma