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ifinatamab deruxtecan   Click here for help

GtoPdb Ligand ID: 13850

Synonyms: DS-7300 | I-DXd
Compound class: Antibody
Comment: Ifinatamab deruxtecan (DS-7300) is a B7-H3 (CD276)-targeting antibody-drug conjugate (ADC) [1]. B7-H3 is an immuno-oncology molecular target in solid tumours. The deruxtecan conjugate is a camptothecin derivative that is used as a cytotoxic DNA topoisomerase 1 payload.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
B7-H3 (CD276) Hs Antibody Binding - - -