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Synonyms: AK-120 | AK120
Compound class:
Antibody
Comment: Manfidokimab (AK120) is a humanized IgG4 monoclonal antibody that targets the IL-4 receptor alpha (IL-4Rα) subunit of the IL-4 and IL-13 receptor complexes. It was designed to block pathological T helper 2 (Th2)-mediated inflammatory responses initiated by the IL-4 and IL-13 cytokines.
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Classification ![]() |
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| Compound class | Antibody |
International Nonproprietary Names ![]() |
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| INN number | INN |
| 11811 | manfidokimab |
Synonyms ![]() |
| AK-120 | AK120 |
Database Links ![]() |
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| Specialist databases | |
| IMGT/mAb-DB | 1198 |
| Other databases | |
| GtoPdb PubChem SID | 513757573 |
| Search PubMed clinical trials | manfidokimab |
| Search PubMed titles | manfidokimab |
| Search PubMed titles/abstracts | manfidokimab |