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Synonyms: AK-111 | AK111
Compound class:
Antibody
Comment: Gumokimab (AK111) is a humanized IgG1 anti-IL-17A monoclonal antibody [2]. It blocks pro-inflammatory cytokine secretion mediated by the IL-17/IL-17 receptor signaling pathway. Based on heavy and light chain CDR sequence matches gumokimab is likely claimed in Akeso's patent EP3805264A1, and is most probably antibody13E9 H3L2 therein [3].
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