RESP-X

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Ligands
RESP-X

GtoPdb Ligand ID: 14217

Synonyms: COT-143 | INFEX702

Compound class: Antibody

Comment: RESP-X is a humanized monoclonal antibody targeting the PcrV protein of Pseudomonas aeruginosa. It is being developed as an anti-virulence therapy for P. aeruginosa infections in patients with non-cystic fibrosis bronchiectasis.

Summary
Biological activity
Clinical data
References

Bioactivity Comments
RESP-X has been studied in a murine P. aeruginosa infection model and shown to inhibit bacterial growth and suppress pro-inflammatory cytokine production in the lungs [1].

Bioactivity Comments

RESP-X has been studied in a murine P. aeruginosa infection model and shown to inhibit bacterial growth and suppress pro-inflammatory cytokine production in the lungs [1].