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RESP-X   Click here for help

GtoPdb Ligand ID: 14217

Synonyms: COT-143 | INFEX702
Compound class: Antibody
Comment: RESP-X is a humanized monoclonal antibody targeting the PcrV protein of Pseudomonas aeruginosa. It is being developed as an anti-virulence therapy for P. aeruginosa infections in patients with non-cystic fibrosis bronchiectasis.
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Summary of Clinical Use Click here for help
A phase 1 study has been registered with the UK's Clinical Study Registry (ID ISRCTN17978477) to evaluate the safety and efficacy of RESP-X in healthy subjects and non-cystic fibrosis bronchiectasis patients colonized with P. aeruginosa.