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posdinemab   Click here for help

GtoPdb Ligand ID: 14292

Synonyms: hPT3 [3] | JNJ-3657 | JNJ-63733657 | JNJ3657 | JNJ63733657
Compound class: Antibody
Comment: Posdinemab (JNJ-63733657) is a humanized IgG1/kappa monoclonal antibody that targets phosphorylated microtubule-associated protein tau. It binds to phosphorylated threonine residues in the protein's proline-rich domain. JNJ-63733657 was humanized from mouse parental antibody PT3 [3]. Phospho-tau reduction is proposed for the treatment of Alzheimer's disease.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11987 posdinemab
Synonyms Click here for help
hPT3 [3] | JNJ-3657 | JNJ-63733657 | JNJ3657 | JNJ63733657
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1280
Other databases
GtoPdb PubChem SID 521588932
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