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rinatabart sesutecan   Click here for help

GtoPdb Ligand ID: 14353

Synonyms: GEN1184 | PRO1184 | Rina-S
Compound class: Antibody
Comment: Rinatabart sesutecan (GEN1184; PRO1184; Rina-S) is a folate receptor alpha (FRα) antibody-drug conjugate. The payload is the topoisomerase I inhibitor exatecan (PubChem CID 151115). Designed to target ovarian and endometrial cancers that are overexpressing FRα.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
folate receptor alpha Hs Antibody Binding - - - 1
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