GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

ATXN2 degron   Click here for help

GtoPdb Ligand ID: 14454

Compound class: Peptide
Comment: This is a fatty acid-modified peptide that acts as a degron (promotes degradation) of the ataxin 2 (ATXN2) protein [1].
Peptide Sequence Click here for help
GRKKRRQRRRGIDIQAVNVVINFDRRRG
Chemical Modification
C16-modified version: Palmitoyl-γGlu linked to the N-terminus of the peptide or
C20-modified version: C20 diacid-γGlu-(AEEA)2 linked to the N-terminus of the peptide, where C20 diacid refers to eicosanedioic acid.