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Compound class:
Peptide
Comment: Cdk5i is a 12 amino acid peptide that corresponds to 148-159 of the T-loop of CDK5. It was designed to prevent formation of the pathological CDK5/p25 complex, in which the truncated p25 isoform of p35 (CDK5R1) acts to hyperactivate CDK5 [1].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
Classification  |
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| Compound class | Peptide |
