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interleukin-17D   Click here for help

GtoPdb Ligand ID: 14474

Synonyms: IL-17D
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: IL-17D is expressed in skeletal muscle, heart, and adipose tissue. In endothelial cells it induces expression of pro-inflammatory cytokines IL-6, IL-8 (CXCL8) and GM-CSF (CSF2) via the NF-κB and MAPK signaling pathways. A functional receptor for IL-17D is proposed to be CD93 (UniProt entry Q8TAD2; CD93) [1-3].
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Synonyms Click here for help
IL-17D
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IL17D interleukin 17D Human interleukin-17D isoform a precursor IL27, interleukin 27
Database Links Click here for help
Ensembl Gene ENSG00000172458 (Hs)
Entrez Gene 53342 (Hs)
GtoPdb PubChem SID 528429795
Human Protein Atlas ENSG00000172458 (Hs)
UniProtKB Q8TAD2 (Hs)