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Compound class:
Peptide
Comment: mM1_034_F21W_Y27F is a peptide agonist of the MAS related GPR family member X1 (MRGPRX1) GPCR [1].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Muratspahić E, Feldman D, Kim DE, Qu X, Bratovianu AM, Rivera-Sánchez P, Voss JH, Hertz EPT, Jeppesen M, Dimitri F et al.. (2026)
De novo design of miniprotein agonists and antagonists targeting G protein-coupled receptors. bioRxiv, Preprint. DOI: 10.1101/2025.03.23.644666 |
