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Synonyms: κ-sparatoxin-Hv1b | κ-SPRTX-Hv1b | HpTX2 | HpTx2 | Toxin KJ6
Compound class:
Peptide
Comment: From Heteropoda venatoria (Brown huntsman spider)
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Ebbinghaus J, Legros C, Nolting A, Guette C, Celerier ML, Pongs O, Bähring R. (2004)
Modulation of Kv4.2 channels by a peptide isolated from the venom of the giant bird-eating tarantula Theraphosa leblondi. Toxicon, 43 (8): 923-32. [PMID:15208026] |
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2. Sanguinetti MC, Johnson JH, Hammerland LG, Kelbaugh PR, Volkmann RA, Saccomano NA, Mueller AL. (1997)
Heteropodatoxins: peptides isolated from spider venom that block Kv4.2 potassium channels. Mol Pharmacol, 51 (3): 491-8. [PMID:9058605] |
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3. Vacher H, Diochot S, Bougis PE, Martin-Eauclaire MF, Mourre C. (2006)
Kv4 channels sensitive to BmTX3 in rat nervous system: autoradiographic analysis of their distribution during brain ontogenesis. Eur J Neurosci, 24 (5): 1325-40. [PMID:16987219] |
