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Synonyms: CnErg1 | CnErgTx1 | ergtoxin | ergtoxin-like protein 1 | ErgTx | ErgTx1 | potassium channel toxin gamma-KTx 1.1
Compound class:
Peptide
Comment: From the venom of Centruroides noxius (Mexican scorpion)
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Müller R, Thiele J, Klages U, Lingens F. (1984)
Incorporation of [18O]water into 4-hydroxybenzoic acid in the reaction of 4-chlorobenzoate dehalogenase from pseudomonas spec. CBS 3. Biochem Biophys Res Commun, 124 (1): 178-82. [PMID:6497878] |
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2. Restano-Cassulini R, Korolkova YV, Diochot S, Gurrola G, Guasti L, Possani LD, Lazdunski M, Grishin EV, Arcangeli A, Wanke E. (2006)
Species diversity and peptide toxins blocking selectivity of ether-a-go-go-related gene subfamily K+ channels in the central nervous system. Mol Pharmacol, 69 (5): 1673-83. [PMID:16497878] |
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3. Shi W, Wymore RS, Wang HS, Pan Z, Cohen IS, McKinnon D, Dixon JE. (1997)
Identification of two nervous system-specific members of the erg potassium channel gene family. J Neurosci, 17 (24): 9423-32. [PMID:9390998] |
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4. Wanke E, Restano-Cassulini R. (2007)
Toxins interacting with ether-à-go-go-related gene voltage-dependent potassium channels. Toxicon, 49 (2): 239-48. [PMID:17097705] |
