Compound class:
Metabolite or derivative
Comment: Riboflavin (vitamin B2) is a water-soluble vitamin that is required for the biosynthesis of flavin-derived enzyme cofactors that are essential for cellular respiration. Taken as a dietary supplement to combat vitamin B2 deficiency.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Kuang W, Zhang J, Lan Z, Deepak RNVK, Liu C, Ma Z, Cheng L, Zhao X, Meng X, Wang W et al.. (2021)
SLC22A14 is a mitochondrial riboflavin transporter required for sperm oxidative phosphorylation and male fertility. Cell Rep, 35 (3): 109025. [PMID:33882315] |
2. Yao Y, Yonezawa A, Yoshimatsu H, Masuda S, Katsura T, Inui K. (2010)
Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain. J Nutr, 140 (7): 1220-6. [PMID:20463145] |