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dulaglutide   Click here for help

GtoPdb Ligand ID: 7638

Synonyms: GLP-1Fc | LY2189265 | Trulicity®
Approved drug
dulaglutide is an approved drug (EMA & FDA (2014))
Compound class: Peptide
Comment: Dulaglutide is a GLP-1 mimetic. This treatment has the benefit of being long-acting, with in vivo studies showing peptide immunoreactivity is detactable >6 days following administration [2]. Therefore dulaglutide requires administration only once a week [1].
No information available.
Summary of Clinical Use Click here for help
Dulaglutide is approved to improve blood sugar levels adults with type 2 diabetes, in conjunction with diet and excercise.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
This synthetic peptide mimics the action of GLP-1 at the GLP-1 receptor.
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT02963766 A Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes Phase 3 Interventional Eli Lilly and Company 1