[125I]-orexin-A   Click here for help

GtoPdb Ligand ID: 9464

 Ligand is labelled  Ligand is radioactive
Comment: A radiolabelled version of orexin-A. Its useful working concentration is in the subnanomolar - low nanomolar range [1-3].
1. Kukkonen JP. (2016)
OX2 orexin/hypocretin receptor signal transduction in recombinant Chinese hamster ovary cells.
Cell Signal, 28 (2): 51-60. [PMID:26582739]
2. Putula J, Pihlajamaa T, Kukkonen JP. (2014)
Calcium affects OX1 orexin (hypocretin) receptor responses by modifying both orexin binding and the signal transduction machinery.
Br J Pharmacol, 171 (24): 5816-28. [PMID:25132134]
3. Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S et al.. (1998)
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.
Cell, 92 (4): 573-85. [PMID:9491897]