Top ▲
GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.
Gene and Protein Information ![]() |
||||||
class A G protein-coupled receptor | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 7 | 342 | 6q23.2 | TAAR8 | trace amine associated receptor 8 | 3 |
Mouse | 7 | 344 | 10 A4 | Taar8b | trace amine-associated receptor 8B | |
Rat | 7 | 344 | 1p12 | Taar8a | trace amine associated receptor 8A |
Previous and Unofficial Names ![]() |
GPR102 | TAR11 | TAR5 | trace amine receptor 5 | trace amine receptor 11 | trace amine receptor 8a | trace amine associated receptor 8 |
Database Links ![]() |
|
Specialist databases | |
GPCRdb | taar8_human (Hs), taa8b_mouse (Mm), taa8a_rat (Rn) |
Other databases | |
Alphafold | Q969N4 (Hs), Q5QD06 (Mm), Q923X9 (Rn) |
ChEMBL Target | CHEMBL4523902 (Hs) |
Ensembl Gene | ENSG00000146385 (Hs), ENSMUSG00000100186 (Mm), ENSRNOG00000070320 (Rn) |
Entrez Gene | 83551 (Hs), 382348 (Mm), 319104 (Rn) |
Human Protein Atlas | ENSG00000146385 (Hs) |
KEGG Gene | hsa:83551 (Hs), mmu:382348 (Mm), rno:319104 (Rn) |
OMIM | 606927 (Hs) |
Pharos | Q969N4 (Hs) |
RefSeq Nucleotide | NM_053278 (Hs), NM_001010837 (Mm), NM_175599 (Rn) |
RefSeq Protein | NP_444508 (Hs), NP_001010837 (Mm), NP_783189 (Rn) |
UniProtKB | Q969N4 (Hs), Q5QD06 (Mm), Q923X9 (Rn) |
Wikipedia | TAAR8 (Hs) |
Tissue Distribution ![]() |
||||||||
|
||||||||
|
||||||||
|
Expression Datasets ![]() |
|
|
Biologically Significant Variants ![]() |
||||||||||||||||||
|
||||||||||||||||||
|
1. Borowsky B, Adham N, Jones KA, Raddatz R, Artymyshyn R, Ogozalek KL, Durkin MM, Lakhlani PP, Bonini JA, Pathirana S et al.. (2001) Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc Natl Acad Sci USA, 98 (16): 8966-71. [PMID:11459929]
2. Chiellini G, Erba P, Carnicelli V, Manfredi C, Frascarelli S, Ghelardoni S, Mariani G, Zucchi R. (2012) Distribution of exogenous [125I]-3-iodothyronamine in mouse in vivo: relationship with trace amine-associated receptors. J Endocrinol, 213 (3): 223-30. [PMID:22442117]
3. Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF. (2001) Discovery and mapping of ten novel G protein-coupled receptor genes. Gene, 275 (1): 83-91. [PMID:11574155]
4. Liberles SD, Buck LB. (2006) A second class of chemosensory receptors in the olfactory epithelium. Nature, 442: 645-650. [PMID:16878137]