Gene and Protein Information
class A G protein-coupled receptor: pseudogene in some individuals
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	7	348	6q23.2	TAAR9	trace amine associated receptor 9
Mouse	7	348	10 A4	Taar9	trace amine-associated receptor 9
Rat	7	338	1p12	Taar9	trace amine-associated receptor 9

Previous and Unofficial Names

TRAR3 | trace amine receptor 3 | trace amine receptor 9 | trace amine associated receptor 9 (gene/pseudogene)

Database Links
Specialist databases
GPCRdb	taar9_human (Hs), taar9_mouse (Mm), taar9_rat (Rn)
Other databases
Alphafold	Q96RI9 (Hs), Q5QD04 (Mm), Q923Y6 (Rn)
ChEMBL Target	CHEMBL4523911 (Hs)
Ensembl Gene	ENSG00000237110 (Hs), ENSMUSG00000037424 (Mm), ENSRNOG00000026096 (Rn)
Entrez Gene	134860 (Hs), 503558 (Mm), 319107 (Rn)
Human Protein Atlas	ENSG00000237110 (Hs)
KEGG Gene	hsa:134860 (Hs), mmu:503558 (Mm), rno:319107 (Rn)
OMIM	608282 (Hs)
Pharos	Q96RI9 (Hs)
RefSeq Nucleotide	NM_175057 (Hs), NM_001010831 (Mm), NM_175602 (Rn)
RefSeq Protein	NP_778227 (Hs), NP_001010831 (Mm), NP_783192 (Rn)
UniProtKB	Q96RI9 (Hs), Q5QD04 (Mm), Q923Y6 (Rn)
Wikipedia	TAAR9 (Hs)

Tissue Distribution
Pituitary gland, skeletal muscle Species:  Human Technique:  Northern blot References:  4
Kidney Species:  Human Technique:  RT-PCR References:  1
Olfactory epithelium Species:  Mouse Technique:  RT-PCR and in situ hybridisation. References:  3
Tissue Distribution Comments
No expression of TAAR9 was detected by RT-PCR in the Grueneberg ganglion [2]. TAAR9 expression was not detected by Northern blot analysis in thalamus, amygdala, midbrain, hippocampus, putamen, caudate, frontal cortex, pons, prostate, stomach, heart, bladder, small intestine, colon or uterus [4].

Expression Datasets
Show »« Hide Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website] There should be a chart of expression data here, you may need to enable JavaScript!

Biologically Significant Variants
Type:  Single nucleotide polymorphism Species:  Human Amino acid change:  A278T Global MAF (%):  3 Subpopulation MAF (%):  AFR|AMR|ASN|EUR: 1|4|2|5 Minor allele count:  A=0.032/69 Comment on frequency:  Low frequency (<10% in all tested populations) SNP accession:  rs9389004 Validation:  1000 Genomes, HapMap, Frequency
Type:  Single nucleotide polymorphism Species:  Human Amino acid change:  S335L Global MAF (%):  3 Subpopulation MAF (%):  AFR|AMR: 11|1 Minor allele count:  T=0.028/60 SNP accession:  rs61741985 Validation:  1000 Genomes, Frequency, Cluster

General Comments
TAAR9 appears to be functional in most individuals but has a polymorphic premature stop codon at amino acid 61 (rs2842899) with an allele frequency of 10–30% in different populations [4].