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Sodium/nucleoside cotransporter 2

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Target not currently curated in GtoImmuPdb

Target id: 1115

Nomenclature: Sodium/nucleoside cotransporter 2

Abbreviated Name: CNT2

Systematic Nomenclature: SLC28A2

Family: SLC28 family

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 14 658 15q21.1 SLC28A2 solute carrier family 28 member 2
Mouse 14 660 2 E5 Slc28a2 solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
Rat 14 659 3q35 Slc28a2 solute carrier family 28 member 2
Previous and Unofficial Names Click here for help
concentrative nucleoside transporter 2 | sodium-coupled nucleoside transporter 2 | sodium/purine nucleoside cotransporter | solute carrier family 28 (concentrative nucleoside transporter), member 2 | solute carrier family 28 (sodium-coupled nucleoside transporter) | solute carrier family 28 (sodium-coupled nucleoside transporter) member 2 | SPNT | SPNT1
Database Links Click here for help
Specialist databases
Bioparadigms SLC Tables SLC28A2 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
Pharos
UniProtKB
Wikipedia
Stoichiometry Click here for help
1 Na+ : 1 nucleoside (in)

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Inhibitors
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Ligand Sp. Action Value Parameter Reference
compound 48 [PMID: 25815140] Small molecule or natural product Hs Inhibition 6.2 pIC50 1
pIC50 6.2 (IC50 6.4x10-7 M) [1]

References

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1. Tatani K, Hiratochi M, Nonaka Y, Isaji M, Shuto S. (2015) Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors. ACS Med Chem Lett, 6 (3): 244-8. [PMID:25815140]

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