Sodium/nucleoside cotransporter 2 | SLC28 family | IUPHAR/BPS Guide to PHARMACOLOGY

Top ▲

Sodium/nucleoside cotransporter 2

Target not currently curated in GtoImmuPdb

Target id: 1115

Nomenclature: Sodium/nucleoside cotransporter 2

Abbreviated Name: CNT2

Systematic Nomenclature: SLC28A2

Family: SLC28 family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - - SLC28A2 solute carrier family 28 member 2
Mouse - - Slc28a2 solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
Rat - - Slc28a2 solute carrier family 28 member 2
Previous and Unofficial Names
concentrative nucleoside transporter 2 | sodium-coupled nucleoside transporter 2 | sodium/purine nucleoside cotransporter | solute carrier family 28 (concentrative nucleoside transporter), member 2 | solute carrier family 28 (sodium-coupled nucleoside transporter) | solute carrier family 28 (sodium-coupled nucleoside transporter) member 2 | SPNT | SPNT1
Database Links
Specialist databases
Bioparadigms SLC Tables SLC28A2 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
1 Na+ : 1 nucleoside (in)

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 48 [PMID: 25815140] Hs Inhibition 6.2 pIC50 1
pIC50 6.2 (IC50 6.4x10-7 M) [1]


Show »

1. Tatani K, Hiratochi M, Nonaka Y, Isaji M, Shuto S. (2015) Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors. ACS Med Chem Lett, 6 (3): 244-8. [PMID:25815140]


Show »

How to cite this page

Select citation format: