Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	512	15q24.1	CYP1A1	cytochrome P450 family 1 subfamily A member 1
Mouse	-	524	9 31.34 cM	Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1
Rat	-	524	8q24	Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1

Previous and Unofficial Names

Aryl hydrocarbon hydroxylase | CP11 | AHH | AHRR | Cyp45c | Cypc45c | cytochrome P450 1A1 | microsomal monooxygenase | xenobiotic monooxygenase | cytochrome P450 subfamily I, polypeptide 1 | cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | cytochrome P450

Database Links
Alphafold	P04798 (Hs), P00184 (Mm), P00185 (Rn)
BRENDA	1.14.1.1
ChEMBL Target	CHEMBL2231 (Hs), CHEMBL6171 (Mm), CHEMBL2922 (Rn)
Ensembl Gene	ENSG00000140465 (Hs), ENSMUSG00000032315 (Mm), ENSRNOG00000019500 (Rn)
Entrez Gene	1543 (Hs), 13076 (Mm), 24296 (Rn)
Human Protein Atlas	ENSG00000140465 (Hs)
KEGG Enzyme	1.14.1.1
KEGG Gene	hsa:1543 (Hs), mmu:13076 (Mm), rno:24296 (Rn)
OMIM	108330 (Hs)
Pharos	P04798 (Hs)
UniProtKB	P04798 (Hs), P00184 (Mm), P00185 (Rn)
Wikipedia	CYP1A1 (Hs)

Enzyme Reaction
EC Number: 1.14.1.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference chrysin Hs Inhibition 7.4 pKi 1 ⤷ pKi 7.4 (Ki 4.2x10-8 M) [1] 5H3'FPE Hs Inhibition 7.4 pIC50 2 ⤷ pIC50 7.4 (IC50 4.3x10-8 M) [2] 65PF Hs Inhibition 6.8 pIC50 2 ⤷ pIC50 6.8 (IC50 1.5x10-7 M) [2]