Top ▲

GPR150

Click here for help

Target not currently curated in GtoImmuPdb

Target id: 136

Nomenclature: GPR150

Family: Class A Orphans

Gene and Protein Information Click here for help
class A G protein-coupled receptor
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 7 434 5q15 GPR150 G protein-coupled receptor 150
Mouse 7 427 13 C1 Gpr150 G protein-coupled receptor 150
Rat 7 - 2q11 Gpr150 G protein-coupled receptor 150
Previous and Unofficial Names Click here for help
PGR11
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Tissue Distribution Click here for help
Central nervous system
Species:  Human
Technique:  Expressed sequence tag
References:  2
Expression Datasets Click here for help

Show »

Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website]

There should be a chart of expression data here, you may need to enable JavaScript!
Biologically Significant Variants Click here for help
Type:  Single nucleotide polymorphism
Species:  Human
Amino acid change:  E214Q
Global MAF (%):  16
Subpopulation MAF (%):  AFR|AMR|ASN|EUR: 3|16|17|22
Minor allele count:  C=0.156/341
SNP accession: 
Validation:  1000 Genomes
General Comments
Abberant methylation of the GPR150 gene may be a candidate tumor marker [1].

References

Show »

1. Cai LY, Abe M, Izumi S, Imura M, Yasugi T, Ushijima T. (2007) Identification of PRTFDC1 silencing and aberrant promoter methylation of GPR150, ITGA8 and HOXD11 in ovarian cancers. Life Sci, 80 (16): 1458-65. [PMID:17303177]

2. Gloriam DE, Schiöth HB, Fredriksson R. (2005) Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship. Biochim Biophys Acta, 1722 (3): 235-46. [PMID:15777626]

Contributors

Show »

How to cite this page