Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	270	12q24.23	PRKAB1	protein kinase AMP-activated non-catalytic subunit beta 1
Mouse	-	270	5 F	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit
Rat	-	270	12q16	Prkab1	protein kinase AMP-activated non-catalytic subunit beta 1

Previous and Unofficial Names

AMPK beta 1 | 5'-AMP-activated protein kinase 40 kDa subunit | AMPKb | protein kinase, AMP-activated, beta 1 non-catalytic subunit | protein kinase

Database Links
Alphafold	Q9Y478 (Hs), Q9R078 (Mm), P80386 (Rn)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL3847 (Hs), CHEMBL3885503 (Rn)
DrugBank Target	Q9Y478 (Hs)
Ensembl Gene	ENSG00000111725 (Hs), ENSMUSG00000029513 (Mm), ENSRNOG00000001142 (Rn)
Entrez Gene	5564 (Hs), 19079 (Mm), 83803 (Rn)
Human Protein Atlas	ENSG00000111725 (Hs)
KEGG Gene	hsa:5564 (Hs), mmu:19079 (Mm), rno:83803 (Rn)
OMIM	602740 (Hs)
Pharos	Q9Y478 (Hs)
RefSeq Nucleotide	NM_006253 (Hs), NM_031869 (Mm), NM_031976 (Rn)
RefSeq Protein	NP_006244 (Hs), NP_114075 (Mm), NP_114182 (Rn)
UniProtKB	Q9Y478 (Hs), Q9R078 (Mm), P80386 (Rn)
Wikipedia	PRKAB1 (Hs)

Download all structure-activity data for this target as a CSV file

Activators
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference MT47-100 Hs Activation 5.4 pKi 1 ⤷ pKi 5.4 (Ki 3.7x10-6 M) [1]