Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	419	7q32.2	CPA1	carboxypeptidase A1
Mouse	-	419	6 12.52 cM	Cpa1	carboxypeptidase A1, pancreatic
Rat	-	419	4q22	Cpa1	carboxypeptidase A1

Previous and Unofficial Names

carboxypeptidase A1 (pancreatic) | carboxypeptidase A1, pancreatic

Database Links
Specialist databases
MEROPS	M14.001 (Hs)
Other databases
Alphafold	P15085 (Hs), Q7TPZ8 (Mm), P00731 (Rn)
BRENDA	3.4.17.1
CATH/Gene3D	3.30.70.340
ChEMBL Target	CHEMBL2088 (Hs)
Ensembl Gene	ENSG00000091704 (Hs), ENSMUSG00000054446 (Mm), ENSRNOG00000010725 (Rn)
Entrez Gene	1357 (Hs), 109697 (Mm), 24269 (Rn)
Human Protein Atlas	ENSG00000091704 (Hs)
KEGG Enzyme	3.4.17.1
KEGG Gene	hsa:1357 (Hs), mmu:109697 (Mm), rno:24269 (Rn)
OMIM	114850 (Hs)
Pharos	P15085 (Hs)
RefSeq Nucleotide	NM_001868 (Hs), NM_025350 (Mm), NM_016998 (Rn)
RefSeq Protein	NP_001859 (Hs), NP_079626 (Mm), NP_058694 (Rn)
UniProtKB	P15085 (Hs), Q7TPZ8 (Mm), P00731 (Rn)
Wikipedia	CPA1 (Hs)

Enzyme Reaction
EC Number: 3.4.17.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference S-BMPA Bt Inhibition 8.1 pKi 2 ⤷ pKi 8.1 (Ki 7.8x10-9 M) [2] compound 1b [PMID: 18078750] Hs Inhibition 6.5 pKi 1 ⤷ pKi 6.5 (Ki 3.1x10-7 M) [1]
View species-specific inhibitor tables