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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 419 | 7q32.2 | CPA1 | carboxypeptidase A1 | |
Mouse | - | 419 | 6 12.52 cM | Cpa1 | carboxypeptidase A1, pancreatic | |
Rat | - | 419 | 4q22 | Cpa1 | carboxypeptidase A1 |
Previous and Unofficial Names ![]() |
carboxypeptidase A1 (pancreatic) | carboxypeptidase A1, pancreatic |
Database Links ![]() |
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Specialist databases | |
MEROPS | M14.001 (Hs) |
Other databases | |
Alphafold | P15085 (Hs), Q7TPZ8 (Mm), P00731 (Rn) |
BRENDA | 3.4.17.1 |
CATH/Gene3D | 3.30.70.340 |
ChEMBL Target | CHEMBL2088 (Hs) |
Ensembl Gene | ENSG00000091704 (Hs), ENSMUSG00000054446 (Mm), ENSRNOG00000010725 (Rn) |
Entrez Gene | 1357 (Hs), 109697 (Mm), 24269 (Rn) |
Human Protein Atlas | ENSG00000091704 (Hs) |
KEGG Enzyme | 3.4.17.1 |
KEGG Gene | hsa:1357 (Hs), mmu:109697 (Mm), rno:24269 (Rn) |
OMIM | 114850 (Hs) |
Pharos | P15085 (Hs) |
RefSeq Nucleotide | NM_001868 (Hs), NM_025350 (Mm), NM_016998 (Rn) |
RefSeq Protein | NP_001859 (Hs), NP_079626 (Mm), NP_058694 (Rn) |
UniProtKB | P15085 (Hs), Q7TPZ8 (Mm), P00731 (Rn) |
Wikipedia | CPA1 (Hs) |
Enzyme Reaction ![]() |
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Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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View species-specific inhibitor tables |
1. Deaton DN, Gao EN, Graham KP, Gross JW, Miller AB, Strelow JM. (2008) Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite. Bioorg Med Chem Lett, 18 (2): 732-7. [PMID:18078750]
2. KIm DH, Kim YJ. (1993) Synthesis and inhibitory activity of optically active 2-benzyl-3-mercaptopropanoic acid against carboxypeptidase A. Bioorg Med Chem Lett, 3 (12): 2681-2684.
M14: Carboxypeptidase A: Carboxypeptidase A1 (pancreatic). Last modified on 29/07/2015. Accessed on 12/02/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1587.