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Target not currently curated in GtoImmuPdb

Target id: 1635

Nomenclature: MMP11

Family: M10: Matrix metallopeptidase

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 488 22q11.23 MMP11 matrix metallopeptidase 11
Mouse - 492 10 38.62 cM Mmp11 matrix metallopeptidase 11
Rat - 491 20p12 Mmp11 matrix metallopeptidase 11
Previous and Unofficial Names Click here for help
SL-3 | ST3 | STMY3 | matrix metallopeptidase 11 (stromelysin 3)
Database Links Click here for help
Specialist databases
MEROPS M10.007 (Hs)
Other databases
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 10 [PMID: 18790648] Small molecule or natural product Primary target of this compound Hs Inhibition 6.6 pKi 1
pKi 6.6 (Ki 2.3x10-7 M) [1]


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1. Georgiadis D, Yiotakis A. (2008) Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg Med Chem, 16 (19): 8781-94. [PMID:18790648]

How to cite this page

M10: Matrix metallopeptidase: MMP11. Last modified on 28/07/2015. Accessed on 18/06/2021. IUPHAR/BPS Guide to PHARMACOLOGY,