MMP11 | M10: Matrix metallopeptidase | IUPHAR/BPS Guide to PHARMACOLOGY

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Target not currently curated in GtoImmuPdb

Target id: 1635

Nomenclature: MMP11

Family: M10: Matrix metallopeptidase

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 488 22q11.23 MMP11 matrix metallopeptidase 11
Mouse - 492 10 C1 Mmp11 matrix metallopeptidase 11
Rat - 491 20p12 Mmp11 matrix metallopeptidase 11
Previous and Unofficial Names
SL-3 | ST3 | STMY3 | matrix metallopeptidase 11 (stromelysin 3)
Database Links
Specialist databases
MEROPS M10.007 (Hs)
Other databases
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 10 [PMID: 18790648] Hs Inhibition 6.6 pKi 1
pKi 6.6 (Ki 2.3x10-7 M) [1]


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1. Georgiadis D, Yiotakis A. (2008) Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg. Med. Chem., 16 (19): 8781-94. [PMID:18790648]

How to cite this page

M10: Matrix metallopeptidase: MMP11. Last modified on 28/07/2015. Accessed on 17/11/2019. IUPHAR/BPS Guide to PHARMACOLOGY,