Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	488	22q11.23	MMP11	matrix metallopeptidase 11
Mouse	-	492	10 38.62 cM	Mmp11	matrix metallopeptidase 11
Rat	-	491	20p12	Mmp11	matrix metallopeptidase 11

Previous and Unofficial Names

SL-3 | ST3 | STMY3 | matrix metallopeptidase 11 (stromelysin 3)

Database Links
Specialist databases
MEROPS	M10.007 (Hs)
Other databases
Alphafold	P24347 (Hs), Q02853 (Mm), Q499S5 (Rn)
BRENDA	3.4.24.-
CATH/Gene3D	3.40.390.10, 2.110.10.10
ChEMBL Target	CHEMBL2867 (Hs), CHEMBL3412 (Mm)
DrugBank Target	P24347 (Hs)
Ensembl Gene	ENSG00000099953 (Hs), ENSMUSG00000000901 (Mm), ENSRNOG00000028344 (Rn)
Entrez Gene	4320 (Hs), 17385 (Mm), 25481 (Rn)
Human Protein Atlas	ENSG00000099953 (Hs)
KEGG Enzyme	3.4.24.-
KEGG Gene	hsa:4320 (Hs), mmu:17385 (Mm), rno:25481 (Rn)
OMIM	185261 (Hs)
Pharos	P24347 (Hs)
RefSeq Nucleotide	NM_005940 (Hs), NM_008606 (Mm), NM_012980 (Rn)
RefSeq Protein	NP_005931 (Hs), NP_032632 (Mm), NP_037112 (Rn)
UniProtKB	P24347 (Hs), Q02853 (Mm), Q499S5 (Rn)
Wikipedia	MMP11 (Hs)

Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference compound 10 [PMID: 18790648] Hs Inhibition 6.6 pKi 1 ⤷ pKi 6.6 (Ki 2.3x10-7 M) [1]