Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	603	12q24.33	MMP17	matrix metallopeptidase 17
Mouse	-	578	5 68.18 cM	Mmp17	matrix metallopeptidase 17
Rat	-	587	12q13	Mmp17	matrix metallopeptidase 17

Previous and Unofficial Names

MT4-MMP | membrane type-4 matrix metalloproteinase | matrix metallopeptidase 17 (membrane-inserted)

Database Links
Specialist databases
MEROPS	M10.017 (Hs)
Other databases
Alphafold	Q9ULZ9 (Hs), Q9R0S3 (Mm), D3ZXJ0 (Rn)
BRENDA	3.4.24.-
CATH/Gene3D	2.110.10.10, 3.40.390.10
ChEMBL Target	CHEMBL2937 (Hs)
DrugBank Target	Q9ULZ9 (Hs)
Ensembl Gene	ENSG00000198598 (Hs), ENSMUSG00000029436 (Mm), ENSRNOG00000023643 (Rn)
Entrez Gene	4326 (Hs), 23948 (Mm), 288626 (Rn)
Human Protein Atlas	ENSG00000198598 (Hs)
KEGG Enzyme	3.4.24.-
KEGG Gene	hsa:4326 (Hs), mmu:23948 (Mm), rno:288626 (Rn)
OMIM	602285 (Hs)
Pharos	Q9ULZ9 (Hs)
RefSeq Nucleotide	NM_016155 (Hs), NM_011846 (Mm), NM_001105925 (Rn)
RefSeq Protein	NP_057239 (Hs), NP_035976 (Mm), NP_001099395 (Rn)
UniProtKB	Q9ULZ9 (Hs), Q9R0S3 (Mm), D3ZXJ0 (Rn)
Wikipedia	MMP17 (Hs)

Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference ilomastat Hs Inhibition 8.5 pIC50 1 ⤷ pIC50 8.5 (IC50 3.4x10-9 M) [1]