Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	562	16p13.3	MMP25	matrix metallopeptidase 25
Mouse	1	615	17 A3.3	Mmp25	matrix metallopeptidase 25
Rat	-	-	10q12	Mmp25	matrix metallopeptidase 25

Previous and Unofficial Names

leukolysin | MT6-MMP | MMP20 | MMPL1

Database Links
Specialist databases
MEROPS	M10.024 (Hs)
Other databases
Alphafold	Q9NPA2 (Hs), Q3U435 (Mm)
BRENDA	3.4.24.-
CATH/Gene3D	2.110.10.10, 3.40.390.10
ChEMBL Target	CHEMBL1795103 (Hs)
DrugBank Target	Q9NPA2 (Hs)
Ensembl Gene	ENSG00000008516 (Hs), ENSMUSG00000023903 (Mm), ENSRNOG00000071032 (Rn)
Entrez Gene	64386 (Hs), 240047 (Mm)
Human Protein Atlas	ENSG00000008516 (Hs)
KEGG Enzyme	3.4.24.-
KEGG Gene	hsa:64386 (Hs), mmu:240047 (Mm)
OMIM	608482 (Hs)
Pharos	Q9NPA2 (Hs)
RefSeq Nucleotide	NM_022468 (Hs), NM_001033339 (Mm)
RefSeq Protein	NP_071913 (Hs), NP_001028511 (Mm)
UniProtKB	Q9NPA2 (Hs), Q3U435 (Mm)
Wikipedia	MMP25 (Hs)

Enzyme Reaction
EC Number: 3.4.24.-

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference CGS-27023A Hs Inhibition 8.8 pIC50 1 ⤷ pIC50 8.8 (IC50 1.5x10-9 M) [1]

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  Cellular signalling