Quaternary Structure: Complexes

Interleukin-21 receptor

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	538	16p12.1	IL21R	interleukin 21 receptor
Mouse	1	529	7 F3	Il21r	interleukin 21 receptor
Rat	-	-		Il21r	interleukin 21 receptor

Previous and Unofficial Names

NILR | CD360

Database Links
Alphafold	Q9HBE5 (Hs), Q9JHX3 (Mm)
CATH/Gene3D	2.60.40.10
Ensembl Gene	ENSG00000103522 (Hs), ENSMUSG00000030745 (Mm), ENSRNOG00000015773 (Rn)
Entrez Gene	50615 (Hs), 60504 (Mm), 308977 (Rn)
Human Protein Atlas	ENSG00000103522 (Hs)
KEGG Gene	hsa:50615 (Hs), mmu:60504 (Mm), rno:308977 (Rn)
OMIM	605383 (Hs)
Pharos	Q9HBE5 (Hs)
UniProtKB	Q9HBE5 (Hs), Q9JHX3 (Mm)
Wikipedia	IL21R (Hs)

Immunopharmacology Comments

This is the ligand binding subunit of the functional heterodimeric receptor for interleukin 21.

Immuno Process Associations

Immuno Process:  Cellular signalling GO Annotations:  Associated to 1 GO processes GO:0030101 natural killer cell activation NAS

Immuno Process:  Cytokine production & signalling GO Annotations:  Associated to 3 GO processes GO:0001532 interleukin-21 receptor activity NAS GO:0004896 cytokine receptor activity IDA GO:0019221 cytokine-mediated signaling pathway IBA