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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 655 | 11p15.4 | NLRP10 | NLR family pyrin domain containing 10 | |
Mouse | - | 673 | 7 E3 | Nlrp10 | NLR family, pyrin domain containing 10 | |
Rat | - | - | 1q33 | Nlrp10 | NLR family, pyrin domain containing 10 |
Previous and Unofficial Names ![]() |
NALP10 | NOD8 | PAN5 | Pynod | NACHT, leucine rich repeat and PYD containing 10 | NLR family, pyrin domain containing 10 | CLR11.1 | NLR family |
Database Links ![]() |
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Alphafold | Q86W26 (Hs), Q8CCN1 (Mm) |
Ensembl Gene | ENSG00000182261 (Hs), ENSMUSG00000049709 (Mm), ENSRNOG00000015082 (Rn) |
Entrez Gene | 338322 (Hs), 244202 (Mm), 293426 (Rn) |
Human Protein Atlas | ENSG00000182261 (Hs) |
KEGG Gene | hsa:338322 (Hs), mmu:244202 (Mm), rno:293426 (Rn) |
OMIM | 609662 (Hs) |
Pharos | Q86W26 (Hs) |
UniProtKB | Q86W26 (Hs), Q8CCN1 (Mm) |
Wikipedia | NLRP10 (Hs) |
Immunopharmacology Comments |
NLRP10 is an intracellular pattern recognition receptor (PRR) that has apoptotic and anti-inflammatory functions [1]. Unlike other other NOD-like receptors, NLRP10 is missing the characteristic leucine-rich repeat domain. |
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Physiological Functions Comments | |
Involved in antigen-presenting cell migration, T-Cell priming and NOD1 signalling enhancement. |