Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	1030	Xp22.13	CDKL5	cyclin dependent kinase like 5
Mouse	-	938	X 73.95 cM	Cdkl5	cyclin dependent kinase like 5
Rat	-	-	X	Cdkl5	cyclin-dependent kinase-like 5

Previous and Unofficial Names

EIEE2 | serine/threonine kinase 9 | STK9

Database Links
Alphafold	O76039 (Hs), Q3UTQ8 (Mm)
BRENDA	2.7.11.22
ChEMBL Target	CHEMBL1163112 (Hs)
Ensembl Gene	ENSG00000008086 (Hs), ENSMUSG00000031292 (Mm), ENSRNOG00000003742 (Rn)
Entrez Gene	6792 (Hs), 382253 (Mm), 100362725 (Rn)
Human Protein Atlas	ENSG00000008086 (Hs)
KEGG Enzyme	2.7.11.22
KEGG Gene	hsa:6792 (Hs), mmu:382253 (Mm), rno:100362725 (Rn)
OMIM	300203 (Hs)
Orphanet	ORPHA119297 (Hs)
Pharos	O76039 (Hs)
RefSeq Nucleotide	NM_001037343 (Hs), NM_001024624 (Mm)
RefSeq Protein	NP_001032420 (Hs), NP_001019795 (Mm)
UniProtKB	O76039 (Hs), Q3UTQ8 (Mm)
Wikipedia	CDKL5 (Hs)

Enzyme Reaction
EC Number: 2.7.11.22

Clinically-Relevant Mutations and Pathophysiology
Disease:  Angelman syndrome Disease Ontology: DOID:1932 OMIM: 105830
Disease:  Atypical Rett syndrome Orphanet: ORPHA3095 References:  1
Disease:  Epileptic encephalopathy, early infantile, 2; EIEE2 Synonyms: Early infantile epileptic encephalopathy [Orphanet: ORPHA1934] Infantile epileptic encephalopathy [Disease Ontology: DOID:2481] Disease Ontology: DOID:2481 OMIM: 300672 Orphanet: ORPHA1934
Disease:  West syndrome Disease Ontology: DOID:0050562 Orphanet: ORPHA3451