Top ▲
Target not currently curated in GtoImmuPdb
Target id: 2220
Nomenclature: serine/threonine kinase 31
Abbreviated Name: STK31
Family: Other-unique family
Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 1019 | 7p15.3 | STK31 | serine/threonine kinase 31 | |
Mouse | - | 1018 | 6 B2.3 | Stk31 | serine threonine kinase 31 | |
Rat | - | 1018 | 4q24 | Stk31 | serine threonine kinase 31 |
Previous and Unofficial Names |
SgK396 | TDRD8 |
Database Links | |
Alphafold | Q9BXU1 (Hs), Q99MW1 (Mm) |
BRENDA | 2.7.11.1 |
ChEMBL Target | CHEMBL6151 (Hs) |
Ensembl Gene | ENSG00000196335 (Hs), ENSMUSG00000023403 (Mm), ENSRNOG00000057554 (Rn) |
Entrez Gene | 56164 (Hs), 77485 (Mm), 500120 (Rn) |
Human Protein Atlas | ENSG00000196335 (Hs) |
KEGG Enzyme | 2.7.11.1 |
KEGG Gene | hsa:56164 (Hs), mmu:77485 (Mm), rno:500120 (Rn) |
OMIM | 605790 (Hs) |
Pharos | Q9BXU1 (Hs) |
RefSeq Nucleotide | NM_031414 (Hs), NM_029916 (Mm), NM_001191971 (Rn) |
RefSeq Protein | NP_113602 (Hs), NP_084192 (Mm), NP_001178900 (Rn) |
UniProtKB | Q9BXU1 (Hs), Q99MW1 (Mm) |
Wikipedia | STK31 (Hs) |
Enzyme Reaction | ||||
|
Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||
|
1. Tao ZF, Chen Z, Bui MH, Kovar P, Johnson E, Bouska J, Zhang H, Rosenberg S, Sowin T, Lin NH. (2007) Macrocyclic ureas as potent and selective Chk1 inhibitors: an improved synthesis, kinome profiling, structure-activity relationships, and preliminary pharmacokinetics. Bioorg Med Chem Lett, 17 (23): 6593-601. [PMID:17935989]
Other-unique family: serine/threonine kinase 31. Last modified on 15/10/2015. Accessed on 06/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2220.