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serine/threonine kinase 31

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Target not currently curated in GtoImmuPdb

Target id: 2220

Nomenclature: serine/threonine kinase 31

Abbreviated Name: STK31

Family: Other-unique family

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 1019 7p15.3 STK31 serine/threonine kinase 31
Mouse - 1018 6 B2.3 Stk31 serine threonine kinase 31
Rat - 1018 4q24 Stk31 serine threonine kinase 31
Previous and Unofficial Names Click here for help
SgK396 | TDRD8
Database Links Click here for help
Alphafold
BRENDA
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 2.7.11.1

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Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 25 [PMID: 17935989] Small molecule or natural product Click here for species-specific activity table Hs Inhibition <5.8 pKi 1
pKi <5.8 (Ki >1.422x10-6 M) [1]

References

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1. Tao ZF, Chen Z, Bui MH, Kovar P, Johnson E, Bouska J, Zhang H, Rosenberg S, Sowin T, Lin NH. (2007) Macrocyclic ureas as potent and selective Chk1 inhibitors: an improved synthesis, kinome profiling, structure-activity relationships, and preliminary pharmacokinetics. Bioorg Med Chem Lett, 17 (23): 6593-601. [PMID:17935989]

How to cite this page

Other-unique family: serine/threonine kinase 31. Last modified on 15/10/2015. Accessed on 23/09/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2220.