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tripartite motif containing 28

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Target not currently curated in GtoImmuPdb

Target id: 2253

Nomenclature: tripartite motif containing 28

Abbreviated Name: TIF1B

Family: TIF1 family

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 835 19q13.43 TRIM28 tripartite motif containing 28
Mouse - 834 7 A1 Trim28 tripartite motif-containing 28
Rat - 835 1q12 Trim28 tripartite motif-containing 28
Previous and Unofficial Names Click here for help
E3 SUMO-protein ligase TRIM28 | KRAB-associated protein 1 | nuclear corepressor KAP-1 | TF1B | TIF1-beta | transcription intermediary factor 1-beta | KRIP-1
Database Links Click here for help
Alphafold
BRENDA
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Selected 3D Structures Click here for help
Image of receptor 3D structure from RCSB PDB
Description:  NMR solution structures of human KAP1 PHD finger-bromodomain.
PDB Id:  2RO1
Resolution:  0.0Å
Species:  Human
References:  1
Enzyme Reaction Click here for help
EC Number: 6.3.2.-
Immuno Process Associations
Immuno Process:  Inflammation
GO Annotations:  Associated to 1 GO processes
GO:0045087 innate immune response IDA
Immuno Process:  Cellular signalling
GO Annotations:  Associated to 1 GO processes
GO:0004842 ubiquitin-protein transferase activity IDA

References

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1. Zeng L, Yap KL, Ivanov AV, Wang X, Mujtaba S, Plotnikova O, Rauscher FJ, Zhou MM. (2008) Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing. Nat Struct Mol Biol, 15 (6): 626-33. [PMID:18488044]

How to cite this page

TIF1 family: tripartite motif containing 28. Last modified on 02/07/2014. Accessed on 28/09/2021. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2253.