VRK serine/threonine kinase 3 | Vaccina related kinase (VRK) family | IUPHAR/BPS Guide to PHARMACOLOGY

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VRK serine/threonine kinase 3

Target not currently curated in GtoImmuPdb

Target id: 2277

Nomenclature: VRK serine/threonine kinase 3

Abbreviated Name: VRK3

Family: Vaccina related kinase (VRK) family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 474 19q13.33 VRK3 VRK serine/threonine kinase 3
Mouse - 453 7 B4 Vrk3 vaccinia related kinase 3
Rat - 453 1 q22 Vrk3 VRK serine/threonine kinase 3
Database Links
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Selected 3D Structures
Image of receptor 3D structure from RCSB PDB
Description:  Structure of VRK3.
Resolution:  2.0Å
Species:  Human
References:  1
Enzyme Reaction
EC Number:


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1. Scheeff ED, Eswaran J, Bunkoczi G, Knapp S, Manning G. (2009) Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site. Structure, 17 (1): 128-38. [PMID:19141289]

How to cite this page

Vaccina related kinase (VRK) family: VRK serine/threonine kinase 3. Last modified on 18/09/2018. Accessed on 09/07/2020. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2277.