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chymotrypsin like elastase 1

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Target not currently curated in GtoImmuPdb

Target id: 2338

Nomenclature: chymotrypsin like elastase 1

Family: S1: Chymotrypsin

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 258 12q13.13 CELA1 chymotrypsin like elastase 1
Mouse - 266 15 56.38 cM Cela1 chymotrypsin-like elastase family, member 1
Rat - 266 7q36 Cela1 chymotrypsin like elastase 1
Previous and Unofficial Names Click here for help
chymotrypsin-like elastase family | chymotrypsin like elastase family member 1 | ELA1 | elastase 1, pancreatic
Database Links Click here for help
Specialist databases
MEROPS S01.153 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
telaprevir Small molecule or natural product Click here for species-specific activity table Hs Inhibition 7.5 pIC50 1
pIC50 7.5 (IC50 3x10-8 M) [1]
Immuno Process Associations
Immuno Process:  Inflammation


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1. Liverton NJ, Carroll SS, Dimuzio J, Fandozzi C, Graham DJ, Hazuda D, Holloway MK, Ludmerer SW, McCauley JA, McIntyre CJ et al.. (2010) MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease. Antimicrob Agents Chemother, 54 (1): 305-11. [PMID:19841155]

How to cite this page

S1: Chymotrypsin: chymotrypsin like elastase 1. Last modified on 27/03/2019. Accessed on 18/07/2024. IUPHAR/BPS Guide to PHARMACOLOGY,