Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	261	19q13.33	KLK3	kallikrein related peptidase 3
Mouse	-	263	7 28.54 cM	Klk1b27	kallikrein 1-related peptidase b27

Previous and Unofficial Names

APS | Gk27 | glandular kallikrein 27 | kallikrein 27 | Prostate-specific antigen | PSA | tissue kallikrein 27 | kallikrein-related peptidase 3

Database Links
Specialist databases
MEROPS	S01.162 (Hs)
Other databases
Alphafold	P07288 (Hs), Q9JM71 (Mm)
BRENDA	3.4.21.77
ChEMBL Target	CHEMBL2099 (Hs)
Ensembl Gene	ENSG00000142515 (Hs), ENSMUSG00000063177 (Mm)
Entrez Gene	354 (Hs), 16619 (Mm)
Human Protein Atlas	ENSG00000142515 (Hs)
KEGG Enzyme	3.4.21.77
KEGG Gene	hsa:354 (Hs), mmu:16619 (Mm)
OMIM	176820 (Hs)
Pharos	P07288 (Hs)
RefSeq Nucleotide	NM_001030047 (Hs), NM_001030048 (Hs), NM_001648 (Hs), NM_020268 (Mm)
RefSeq Protein	NP_001639 (Hs), NP_001025219 (Hs), NP_001025218 (Hs), NP_064664 (Mm)
UniProtKB	P07288 (Hs), Q9JM71 (Mm)
Wikipedia	KLK3 (Hs)

Enzyme Reaction
EC Number: 3.4.21.77

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference compound 20 [PMID: 23692593] Hs Inhibition 7.1 pKi 1 ⤷ pKi 7.1 (Ki 7.2x10-8 M) [1] Description: PSA isolated from human seminal plasma.