pancreatic lipase | Hydrolases | IUPHAR/BPS Guide to PHARMACOLOGY

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pancreatic lipase

Target not currently curated in GtoImmuPdb

Target id: 2590

Nomenclature: pancreatic lipase

Abbreviated Name: PNLIP

Family: Hydrolases

Annotation status:  image of an orange circle Annotated and awaiting review. Please contact us if you can help with reviewing.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 465 10q26.1 PNLIP pancreatic lipase
Mouse - 465 19 D2 Pnlip pancreatic lipase
Rat - 465 1q55 Pnlip pancreatic lipase
Previous and Unofficial Names
pancreatic triacylglycerol lipase | pancreatic triglyceride lipase | PANLI | PL
Database Links
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
orlistat Hs Inhibition 8.9 pIC50 1
pIC50 8.9 (IC50 1.3x10-9 M) [1]


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1. Bustanji Y, Issa A, Mohammed M, Hudaib M, Tawah, K, Alkhatib H, Almarsi I, Al-Khalidi B. (2010) Inhibition of hormone sensitive lipase and pancreatic lipase by Rosmarinus officinalis extract and selected phenolic constituents. Journal of Medicinal Plants Research, 4 (21): 2235-2242.

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